Four hepatosplenic T-cell lymphoma cases of Japanese patients

Publication date: 2016 Source:Leukemia Research Reports, Volume 5 Author(s): Hidetsugu Kawai, Hiromichi Matsushita, Ken Ohmachi, Minoru Kojima, Shinichiro Machida, Yoshiaki Ogawa, Hiroshi Kawada, Naoya Nakamura, Kiyoshi Ando Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.
Source: Leukemia Research Reports - Category: Hematology Source Type: research