A polyphenol-Rich Fraction Obtained from table grapes decreases adiposity, insulin resistance, and markers of inflammation and impacts gut microbiota in high-fat fed mice

The objective of this study was to determine if consuming an extractable or non-extractable fraction of table grapes reduced the metabolic consequences of consuming a high-fat, American-type diet. Male C57BL/6J mice were fed a low fat (LF) diet, a high fat (HF) diet, or a HF diet containing whole table grape powder (5% w/w), an extractable, polyphenol-rich (HF-EP) fraction, a non-extractable, polyphenol-poor (HF-NEP) fraction, or equal combinations of both fractions (HF-EP+NEP) from grape powder for 16weeks.

Source: The Journal of Nutritional Biochemistry - February 25, 2016 Category: Biochemistry Authors: Brian Collins, Jessie Hoffman, Kristina Martinez, Mary Grace, Mary Ann Lila, Chase Cockrell, Anuradha Nadimpalli, Eugene Chang, Chia-Chi Chuang, Wei Zhong, Jessica Mackert, Wan Shen, Paula Cooney, Robin Hopkins, Michael McIntosh Source Type: research