The RSK Inhibitor BIX02565 Limits Cardiac Ischemia/Reperfusion Injury

Conclusion:
The RSK plays a crucial role in I/R-induced activation of NHE1 and cardiac injury. The RSK inhibition may provide an alternative target for patients with MI.

Source: Journal of Cardiovascular Pharmacology and Therapeutics - February 24, 2016 Category: Cardiology Authors: Shi, X., ONeill, M. M., MacDonnell, S., Brookes, P. S., Yan, C., Berk, B. C. Tags: Experimental Studies Source Type: research