Role of BRAF and RAS Mutations in Extrathyroidal Extension in Papillary Thyroid Cancer

Conclusion: BRAF V600E mutation predisposes PTC cells toward invasive phenotypes, while RAS mutation confers resistance to ETE. The differential regulation appears to be mediated through WNT4.

Source: Cancer Genomics and Proteomics - February 24, 2016 Category: Cancer & Oncology Authors: PARK, J. Y., YI, J. W., PARK, C. H., LIM, Y., LEE, K. H., LEE, K. E., KIM, J. H. Tags: Article Source Type: research