Doxorubicin Treatment of Cancer Cells Impairs Reverse Transcription and Affects the Interpretation of RT-qPCR Results

Conclusion: DOX may alter the reverse transcription and amplification reactions of RT-qPCR, thus creating a risk of misinterpretation of gene expression results.

Source: Cancer Genomics and Proteomics - February 24, 2016 Category: Cancer & Oncology Authors: DROZD, E., KRZYSZTOŃ-RUSSJAN, J., GRUBER, B. Tags: Article Source Type: research