Mechanistic Study of Inhibitory Effects of Atorvastatin and Docetaxel in Combination on Prostate Cancer

Conclusion: Treatment with cholesterol decreased the sensitivity of prostate cancer cells to docetaxel. Docetaxel in combination with cholesterol-lowering drugs such as atorvastatin may be an effective strategy for inhibiting the growth of prostate cancer.

Source: Cancer Genomics and Proteomics - February 24, 2016 Category: Cancer & Oncology Authors: CHEN, X., LIU, Y., WU, J., HUANG, H., DU, Z., ZHANG, K., ZHOU, D., HUNG, K., GOODIN, S., ZHENG, X. Tags: Article Source Type: research