Na+/H+ exchanger 1, Na+/Ca2+ exchanger 1 and calmodulin complex regulates interleukin 6-mediated cellular behavior of human hepatocellular carcinoma

In conclusion, IL6 activates the functional activity of NHE1 and induces the functional and structural interaction of NHE1, NCX1 and CaM. The interaction of NHE1, NCX1 and CaM mediates the effects of IL6 on human HCC.

Source: Carcinogenesis - February 24, 2016 Category: Cancer & Oncology Authors: Xu, J., Ji, B., Wen, G., Yang, Y., Jin, H., Liu, X., Xie, R., Song, W., Song, P., Dong, H., Tuo, B. Tags: Original Manuscript Source Type: research