Comparison of the effect of negative pressure wound therapy with and without installation of polyhexanide on the bacterial kinetic in chronic wounds

Conclusion It was demonstrated that management of infected wounds with NPWT, with or without instillation of 0.02% PHMB, did not reduce the number of bacteria on wounds. Bacteria proliferate below a NPWT dressing and increase in numbers. Independently of bacterial kinetics, all wounds showed excellent granulation and healed with no complications. This observation challenges the concept that bacterial bioburden correlates with impaired wound healing. [Vergleichende Untersuchung des Effektes der Unterdruck-Wundtherapie mit und ohne Instillation von Polyhexanid auf die bakterielle Kinetik in chronischen Wunden]
Source: Wound Medicine - Category: Journals (General) Source Type: research