Cutaneous Manifestations in Neuro-Oncology: Clinically Relevant Tumor and Treatment Associated Dermatologic Findings

Skin findings are a rare but important aspect of the evaluation and management of patients with tumors of the nervous system. Skin findings have the highest prevalence in genetic tumor syndromes termed neuro-genodermatoses which include neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2), and tuberous sclerosis. Skin changes are observed in patients with non-syndromic nervous system malignancy often as a result of pharmacotherapy. The skin may also manifest findings in paraneoplastic conditions that affect the nervous system providing an early indication of underlying neoplasm, including dermatomyosistis, neuropathic itch, and brachioradial pruritus.
Source: Seminars in Oncology - Category: Cancer & Oncology Authors: Source Type: research