A High-Content Imaging Screen for Cellular Regulators of {beta}-Catenin Protein Abundance

This study demonstrates that detecting cell-based β-catenin protein stability is a viable approach to identifying novel mechanisms of β-catenin regulation as well as small molecules of therapeutic potential.

Source: Journal of Biomolecular Screening - February 19, 2016 Category: Molecular Biology Authors: Zeng, X., Montoute, M., Bee, T. W., Lin, H., Kallal, L. A., Liu, Y., Agarwal, P., Wang, D., Lu, Q., Morrow, D., Pope, A. J., Wu, Z. Tags: Original Research Source Type: research