Differentiation of benign from malignant follicular-cell-derived thyroid lesions: an immunohistochemical study

Conclusion: Combined use of markers such as galectin-3 and CK-19 and IMP-3 did not markedly increase the sensitivity or specificity over using a single marker. Each studied marker has sensitivity and specificity for certain thyroid lesion. Immunohistochemical stains of galectin-3, CK-19, and IMP-3, especially when used in combination, can be a useful adjunct in the histopathological diagnoses of thyroid lesions.
Source: Egyptian Journal of Pathology - Category: Pathology Tags: Original Articles Source Type: research