Management of Differentiated Thyroid Cancer in Children: Focus on the American Thyroid Association Pediatric Guidelines

First introduced in 1946, radioactive iodine (I-131) produces short-range beta radiation with a half-life of 8 days. The physical properties of I-131 combined with the high degree of uptake in the differentiated thyroid cancers (DTCs) led to the use of I-131 as a therapeutic agent for DTC in adults. There are two indications for the potential use of I-131 therapy in pediatric thyroid disorders: nonsurgical treatment of hyperthyroidism owing to Graves’ disease and the treatment of children with intermediate- and high-risk DTC.

Source: Seminars in Nuclear Medicine - February 19, 2016 Category: Nuclear Medicine Authors: Marguerite T. Parisi, Hedieh Eslamy, David Mankoff Source Type: research