Mitochondrial involvement in propofol-induced cardioprotection: An in vitro study in human myocardium

In conclusion, in human myocardium, propofol-induced cardioprotection was mediated by mitochondrial adenosine triphosphate-sensitive potassium channels opening, nitric oxide synthase activation and stimulation of mitochondrial respiratory chain complexes, in early reoxygenation period.

Source: Experimental Biology and Medicine - February 16, 2016 Category: Research Authors: Lemoine, S., Zhu, L., Gress, S., Gerard, J.-L., Allouche, S., Hanouz, J.-L. Tags: Pharmacology/Toxicology Source Type: research