Possible involvement of the JAK/STAT signaling pathway in N-acetylcysteine-mediated antidepressant-like effects

In conclusion, our study suggests that modulation of the JAK/STAT pathway might mediate the antidepressant-like effects of N-acetylcysteine. Therefore, depression research may target the JAK/STAT signaling pathway to provide a novel effective therapy.

Source: Experimental Biology and Medicine - February 16, 2016 Category: Research Authors: Al-Samhari, M. M., Al-Rasheed, N. M., Al-Rejaie, S., Al-Rasheed, N. M., Hasan, I. H., Mahmoud, A. M., Dzimiri, N. Tags: Pharmacology/Toxicology Source Type: research