A comparative investigation of methods for longitudinal data with limits of detection through a case study

In conclusion, the antiretroviral treatment was associated with a significant decrease in viral load after controlling the effects of other covariates. A simulation study with finite sample size shows MCEM is the least biased method and the estimates are least sensitive to the censoring mechanism.

http://smm.sagepub.com/cgi/content/abstract/25/1/153?rss=1

Source: Statistical Methods in Medical Research - February 16, 2016 Category: Statistics Authors: Fu, P., Hughes, J., Zeng, G., Hanook, S., Orem, J., Mwanda, O., Remick, S. Tags: Articles Source Type: research