Response-adaptive designs for continuous treatment responses in phase III clinical trials: A review

A variety of response-adaptive randomization procedures have been proposed in literature assuming binary outcomes. However, the list is not so long for continuous outcomes though many real clinical trials deal with continuous treatment responses. In this paper, we attempt to explore the available procedures together with a comparison of their performances. Some real-life adaptive trial is also reviewed.
Source: Statistical Methods in Medical Research - Category: Statistics Authors: Tags: Articles Source Type: research