Short peptides from leucyl-tRNA synthetase rescue disease-causing mitochondrial tRNA point mutations
In conclusion, we demonstrate that small Cterm-derived peptides can be effective tools to rescue cellular defects caused by mutations in a wide range of mt-tRNAs.
Source: Human Molecular Genetics - Category: Genetics & Stem Cells Authors: Perli, E., Fiorillo, A., Giordano, C., Pisano, A., Montanari, A., Grazioli, P., Campese, A. F., Di Micco, P., Tuppen, H. A., Genovese, I., Poser, E., Preziuso, C., Taylor, R. W., Morea, V., Colotti, G., d'Amati, G. Tags: ARTICLES Source Type: research
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