Gastroschisis in a fetus with a congenital neuroblastoma: Association or coincidence?

ConclusionWe cannot rule out the possibility that a clotting defect, commonly observed in disseminated malignancies such as a metastatic neuroblastoma may be associated with the etiology of the gastroschisis, as this defect may result from a thrombosis occurring around 3 to 4 weeks of gestation, a period when neuroblasts development occurs into the adrenal medulla. However, we cannot exclude the possibility that both events may have occurred simultaneously by chance. Birth Defects Research (Part A), 2016. © 2016 Wiley Periodicals, Inc.

Source: Birth Defects Research Part A: Clinical and Molecular Teratology - February 1, 2016 Category: Perinatology & Neonatology Authors: Rafael F.M. Rosa, Laura Michelon, Átila Masiero, Adyr E.V. Faria, Vanessa F. De Souza, Cristine Dietrich, Luciano V. Targa, Valentina O. Provenzi, Silvana R.S. Pires, Paulo R.G. Zen Tags: Research Article Source Type: research