Promoter polymorphism at the tumour necrosis factor/lymphotoxin-alpha locus is associated with type of diabetes but not with susceptibility to sight-threatening diabetic retinopathy

Conclusion:
An association between the A allele of rs1800629 and type of diabetes was found. No association was found between two promoter variants of TNF and LTA, and diabetic retinopathy in a large cohort of Caucasian patients with type 1 diabetes and type 2 diabetes.

Source: Diabetes and Vascular Disease Research - February 12, 2016 Category: Endocrinology Authors: Kaidonis, G., Craig, J. E., Gillies, M. C., Abhary, S., Essex, R. W., Chang, J. H., Pal, B., Pefkianaki, M., Daniell, M., Lake, S., Petrovsky, N., Burdon, K. P. Tags: Brief Report Source Type: research