Combined ultrasound targeted microbubble destruction and Polyethylenimine mediated plasmid DNA delivery to rat retina: enhanced efficiency and accelerated expression

ConclusionsThe key advantage of this article is that enhanced and accelerated pDNA expression can be achieved in the retina/ retinal pigment epithelium (RPE) cells in vivo by UTMD physical techniques combined with PEI chemical vector. This study provides useful basic information for further in vivo retinal gene therapy work. This article is protected by copyright. All rights reserved.
Source: The Journal of Gene Medicine - Category: Genetics & Stem Cells Authors: Tags: Research Article Source Type: research