Improved Murine Blastocyst Quality and Development in a Single Culture Medium Compared to Sequential Culture Media

Conclusions:
Single medium yields greater cell numbers, an increased growth rate, and more hatching of murine embryos. Cytoplasmic UCHL1 and nuclear UHCL3 localization patterns were indicative of embryo quality. Our conclusions are limited to murine embryos but one might speculate that single medium may also be more beneficial for human embryo culture. Human embryo studies are needed.

Source: Reproductive Sciences - February 8, 2016 Category: Reproduction Medicine Authors: Hennings, J. M., Zimmer, R. L., Nabli, H., Davis, J. W., Sutovsky, P., Sutovsky, M., Sharpe-Timms, K. L. Tags: Original Articles Source Type: research