Characterization of a new HLA‐A allele, HLA‐A*02:07:08, by cloning and sequencing

In this report, we present a novel HLA‐A*02:07 allele, HLA‐A*02:07:08. HLA‐A*02:07:08 was identified in an individual of Han ethnicity in Hunan province, southern China. Following polymerase chain reaction‐sequence‐based typing (PCR‐SBT), this new allele was further confirmed by cloning and sequencing. HLA‐A*02:07:08 differs from HLA‐A*02:07:01 by a single synonymous C to T substitution at nucleotide position 131 in exon 3.

Source: International Journal of Immunogenetics - February 1, 2016 Category: Genetics & Stem Cells Authors: W. Y. Wang, W. Zhang, L. X. Li, F. M. Zhu, W. Tian Tags: Short Communication Source Type: research