TOPBP1 missense variant Arg309Cys and breast cancer in a German hospital-based case-control study

The DNA double strand break repair gene TOPBP1 has been suggested as a breast cancer susceptibility gene and a missense variant Arg309Cys was observed at elevated frequency in familial breast cancer cases compare...

Source: Journal of Negative Results in BioMedicine - November 25, 2010 Category: Research Authors: Magda A Blaut, Natalia V Bogdanova, Michael Bremer, Johann H Karstens, Peter Hillemanns and Thilo Dörk Source Type: research