Citalopram for the Treatment of Agitation in Alzheimer Dementia: Genetic Influences

Discussion:
Treatment outcomes in CitAD showed modest, although statistically significant, influence of genetic variation at HTR2A and HTR2C loci. Future studies should continue to examine the interaction of known genetic variants with antidepressant treatment in patients with AD having agitation.

Source: Journal of Geriatric Psychiatry and Neurology - February 8, 2016 Category: Genetics & Stem Cells Authors: Peters, M. E., Vaidya, V., Drye, L. T., Devanand, D. P., Mintzer, J. E., Pollock, B. G., Porsteinsson, A. P., Rosenberg, P. B., Schneider, L. S., Shade, D. M., Weintraub, D., Yesavage, J., Lyketsos, C. G., Avramopoulos, D., For the CitAD Research Group Tags: Articles Source Type: research