Insulin-Like Growth Factor-I is a Marker for the Nutritional State.

Insulin-Like Growth Factor-I is a Marker for the Nutritional State. Pediatr Endocrinol Rev. 2015 Dec;13(2):499-511 Authors: Hawkes CP, Grimberg A Abstract Measurement of the serum concentration of insulin-like growth factor-I (IGF-l) is generally used as a screening investigation for disorders of the growth hormone (GH)/IGF-I axis in children and adolescents with short stature. IGF-I concentration is sensitive to short-term and chronic alterations in the nutritional state, and the interpretation of IGF-I measurements requires knowledge of the child's nutritional status. In this review, we summarize the effects of nutrition on the GH/IGF-I axis, and review the clinical implications of these interactions throughout childhood, both in under-nutrition and over-nutrition. PMID: 26841638 [PubMed - in process]
Source: Pediatric Endocrinology Reviews - Category: Endocrinology Tags: Pediatr Endocrinol Rev Source Type: research