Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15

This study shows that GDF-15 levels are associated with differences in DNA methylation in blood cells, and a subset of the loci are also differentially methylated in participants with MI. However, there might be interactions between GDF-15 levels and methylation in other tissues not addressed in this study. These results provide novel links between GDF-15 and cardiovascular disease.

Source: Human Molecular Genetics - February 5, 2016 Category: Genetics & Stem Cells Authors: Ek, W. E., Hedman, A. K., Enroth, S., Morris, A. P., Lindgren, C. M., Mahajan, A., Gustafsson, S., Gyllensten, U., Lind, L., Johansson, A. Tags: ASSOCIATION STUDIES ARTICLES Source Type: research