Ruminant and Industrial Trans Fatty Acid Uptake in the Heart

Dietary trans fats are strongly associated with heart disease. However, the capacity for the tissues of the body, and specifically the heart, to take up trans fats is unknown. It is also unknown if different trans fats have different uptake capacities in the heart and other tissues of the body. Diets of low density lipoprotein receptor deficient mice were supplemented for 14 weeks with foods that contained 1.5% of the trans fat elaidic acid or vaccenic acid. Tissues were extracted, frozen in liquid nitrogen and then lipids were analyzed by gas chromatography for fatty acid content.
Source: The Journal of Nutritional Biochemistry - Category: Biochemistry Authors: Source Type: research