Extrathoracic investigation in adult patients with isolated pulmonary langerhans cell histiocytosis

Conclusions:
Obtaining a thorough history and performing comprehensive physical examination are essential for staging patients diagnosed with PLCH. In the absence of symptoms or signs suggestive of extrapulmonary LCH involvement, the systematic performing of recommended bone imaging does not appear informative. Although the observed blood laboratory abnormalities were not specifically related to LCH, performing these tests in the diagnostic workup for PLCH is useful because some of these alterations may impact patient management.Trial registrationClinicalTrials.gov: No. NCT01225601; URL: www.clinicaltrials.gov

Source: Epidemiologic Perspectives and Innovations - February 2, 2016 Category: Epidemiology Authors: Abdellatif TaziConstance de Margerie-MellonLaetitia VercellinoJean NaccacheStéphanie FryStéphane DominiqueStéphane JouneauGwenaël LorillonEmmanuelle BugnetRaphael ChironBenoit WallaertDominique ValeyreSylvie Chevret Source Type: research