Microstructure of the Midbrain and Cervical Spinal Cord in Idiopathic Restless Legs Syndrome: A Diffusion Tensor Imaging Study

Conclusions:The imaging data suggest that significant alterations in the midbrain in RLS can be visualized by DTI and might correlate to a macroscopically subtle process with changes of the tissue microstructure in the corresponding tracts. An additional area of interest is regionally clustered in the upper cervical spinal cord with a tendency toward altered diffusion metrics. These results might be addressed by further studies, e.g., at higher magnetic field strengths.Citation:Lindemann K, Müller HP, Ludolph AC, Hornyak M, Kassubek J. Microstructure of the midbrain and cervical spinal cord in idiopathic restless legs syndrome: a diffusion tensor imaging study. SLEEP 2016;39(2):423–428.
Source: Sleep - Category: Sleep Medicine Source Type: research