A Four-Year Longitudinal Study on Restless Legs Syndrome in Parkinson Disease

Conclusions:RLS is present since PD diagnosis, and increases in prevalence during the course of PD. PD subjects with RLS have higher age at PD onset, more preserved dopaminergic pathways, and worse sleep and cardiovascular disturbances.Citation:Moccia M, Erro R, Picillo M, Santangelo G, Spina E, Allocca R, Longo K, Amboni M, Palladino R, Assante R, Pappatà S, Pellecchia MT, Barone P, Vitale C. A four-year longitudinal study on restless legs syndrome in Parkinson disease. SLEEP 2016;39(2):405–412.
Source: Sleep - Category: Sleep Medicine Source Type: research