Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice

Conclusion:Dual orexin receptor antagonists may be an effective sleeping aid in epilepsy, and warrants further study on their somnogenic and ant-seizure effects in other epilepsy models.Citation:Roundtree HM, Simeone TA, Johnson C, Matthews SA, Samson KK, Simeone KA. Orexin receptor antagonism improves sleep and reduces seizures in Kcna1-null mice. SLEEP 2016;39(2):357–368.

http://www.journalsleep.org/ViewAbstract.aspx?pid=30437

Source: Sleep - January 31, 2016 Category: Sleep Medicine Source Type: research