Vanadium inhalation induces actin changes in mice testicular cells

We reported immunohistochemical changes in actin testicular cytoskeleton in a vanadium inhalation experimental mice model. Our findings show that exposure to vanadium pentoxide (0.02 M) results in actin decrease in testicular cells from 3–12 weeks exposure time; this effect was statistically significant and exposure time dependent. Actin cytoskeleton damage is a mechanism that could explain vanadium reprotoxic effects and its association with impaired fertility.
Source: Toxicology and Industrial Health - Category: Toxicology Authors: Tags: Articles Source Type: research