HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients

Conclusions:
HPV contribution to HNCs is substantial but highly heterogeneous by cancer site, region, and sex. This study, the largest exploring HPV attribution in HNCs, confirms the important role of HPVs in oropharyngeal cancer and drastically downplays the previously reported involvement of HPVs in the other HNCs.

Source: JNCI - January 28, 2016 Category: Cancer & Oncology Authors: Castellsague, X., Alemany, L., Quer, M., Halec, G., Quiros, B., Tous, S., Clavero, O., Alos, L., Biegner, T., Szafarowski, T., Alejo, M., Holzinger, D., Cadena, E., Claros, E., Hall, G., Laco, J., Poljak, M., Benevolo, M., Kasamatsu, E., Mehanna, H., Ndia Tags: Article Source Type: research