An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes

In conclusion, in this mouse model cessation or switching to THS2.2 retarded the progression of CS-induced atherosclerotic and emphysematous changes, while THS2.2 aerosol alone had minimal adverse effects.

Source: Toxicological Sciences - January 25, 2016 Category: Toxicology Authors: Phillips, B., Veljkovic, E., Boue, S., Schlage, W. K., Vuillaume, G., Martin, F., Titz, B., Leroy, P., Buettner, A., Elamin, A., Oviedo, A., Cabanski, M., De Leon, H., Guedj, E., Schneider, T., Talikka, M., Ivanov, N. V., Vanscheeuwijck, P., Peitsch, M. C Tags: Evaluation of Cardiovascular and Respiratory Toxicity of Non-Burn Tobacco Source Type: research