Ovarian follicle development in vitro and oocyte competence: advances and challenges for farm animals

During the last 2 decades, research on in vitro preantral follicle growth and oocyte maturation has delivered fascinating advances concerning the knowledge of processes regulating follicle growth and the developmental competence of oocytes. These advances include (1) information about the role of several hormones and growth factors on in vitro activation of primordial follicles; (2) increased understanding of the intracellular pathway involved in the initiation of primordial follicle growth; (3) the growth of primary and secondary follicles up to antral stages; and (4) production of embryos from oocytes from in vitro grown preantral follicles.

Source: Domestic Animal Endocrinology - January 6, 2016 Category: Endocrinology Authors: J.R.V. Silva, R. van den Hurk, J.R. Figueiredo Source Type: research