Injection of Human Cord Blood Cells With Hyaluronan Improves Postinfarction Cardiac Repair in Pigs

This study using healthy human cord blood mononuclear cells (CB-MNCs) to treat myocardial infarction provides preclinical evidence that combined injection of hyaluronan and human CB-MNCs after myocardial infarction significantly increases cell retention in the peri-infarct area, improves cardiac performance, and prevents cardiac remodeling. Moreover, using healthy cells to replace dysfunctional autologous cells may constitute a better strategy to achieve heart repair and regeneration.

Source: Stem Cells Translational Medicine - January 7, 2016 Category: Stem Cells Authors: Chang, M.-Y., Huang, T.-T., Chen, C.-H., Cheng, B., Hwang, S.-M., Hsieh, P. C. H. Tags: Enabling Technologies for Cell-Based Clinical Translation, Cord Blood Stem Cells Source Type: research