Randomized controlled trial of the CGRP receptor antagonist telcagepant for prevention of headache in women with perimenstrual migraine

Conclusions Telcagepant 140 mg taken perimenstrually for seven days was generally well tolerated, but was associated with transaminase elevations. Telcagepant did not reduce monthly headache frequency, but did reduce perimenstrual headaches.

http://cep.sagepub.com/cgi/content/abstract/36/2/148?rss=1

Source: Cephalalgia - January 18, 2016 Category: Neurology Authors: Ho, T. W., Ho, A. P., Ge, Y., Assaid, C., Gottwald, R., MacGregor, E. A., Mannix, L. K., van Oosterhout, W. P., Koppenhaver, J., Lines, C., Ferrari, M. D., Michelson, D. Tags: February 2016 36 (2) Original Articles Source Type: research