Recent Treatments of Interstitial Lung Disease with Systemic Sclerosis

Systemic sclerosis (SSc) is a disorder characterized by immune dysfunction, microvascular injury, and fibrosis. Organ involvement in patients with SSc is variable; however, pulmonary involvement occurs in up to 90% of patients with SSc. Interstitial lung disease (ILD) is a major cause of mortality and, thus, a major determinant in the prognosis of patients with SSc. This review summarizes current findings about the characteristics of ILD in patients with SSc, selection of patients with SSc-ILD who are candidates for the treatment, and current treatment options.
Source: Clinical Medicine Insights: Circulatory, Respiratory and Pulmonary Medicine - Category: Respiratory Medicine Authors: Source Type: research