Methotrexate and actinomycin D chemotherapy in a patient with porphyria: a case report

Conclusions: Methotrexate and actinomycin D did not induce acute porphyric attacks in this patient with acute intermittent porphyria; however, severe adverse effects were noted with methotrexate. Although further investigation is required, our data suggest that these agents are nonporphyrinogenic and can therefore be used to treat patients with comorbid porphyria.
Source: Epidemiologic Perspectives and Innovations - Category: Epidemiology Authors: Source Type: research