Cord Blood Versus Haploidentical Stem Cell Transplantation for Hematological Malignancies

Umbilical cord blood and haploidentical donor stem cell sources represent common alternative donor strategies utilized when a matched sibling or unrelated donor are not available for hematopoietic stem cell transplantation. Both donor sources require less stringent HLA matching and thereby increase the donor pool for patients without a complete HLA matched donor. Although a randomized trial comparing these donor sources is ongoing, currently available comparisons rely on observational data and small phase II trials.
Source: Seminars in Hematology - Category: Hematology Authors: Source Type: research