Mismatched Unrelated Alternative Donors for Hematological Malignancies

For the majority of hematologic malignancies allogeneic hematopoietic cell transplantation (HCT) is the only curative treatment option. Sibling donors have been the standard for adult patients. Since there is not a suitable family donor for all patients, the need for alternative donors for HCT is great. Fortunately the availability of unrelated volunteer donor registries have expanded over the years and the results of HCT with matched unrelated donors (MUD) are comparable to the results with matched related donors (MRD).
Source: Seminars in Hematology - Category: Hematology Authors: Source Type: research