Echocardiographic Endpoints in Pediatric Cardiomyopathy and Heart Failure Trials

In clinical research, the desired result of an intervention typically involves improvement in one or more of the following clinically meaningful outcomes: increasing long-term survival, reducing risk of hospitalization/re-hospitalization, improving quality of life, and improving functional status. The very nature of these long-term, clinically meaningful outcomes limits their use in the research setting, however, and many studies rely on surrogate endpoints or composite endpoints which combine the two.
Source: Progress in Pediatric Cardiology - Category: Cardiology Authors: Tags: Review Source Type: research