Resveratrol attenuates renal injury and fibrosis by inhibiting transforming growth factor-{beta} pathway on matrix metalloproteinase 7

In conclusion, RSV attenuated renal injury and fibrosis by inhibiting EMT process which was attributed to the fact that the up-regulated SIRT1 by RSV deacetylated Smad4 and inhibited MMP7 expression.

Source: Experimental Biology and Medicine - January 13, 2016 Category: Research Authors: Xiao, Z., Chen, C., Meng, T., Zhang, W., Zhou, Q. Tags: Biochemistry & amp;amp; Molecular Biology Source Type: research