Conjugated Linoleic Acid Mitigates Testosterone-Related Changes in Body Composition in Male Guinea Pigs

We hypothesize that conjugated linoleic acid (CLA) may be effective in preventing the changes in total and regional body composition, and increases in interleukin (IL) -6 that occur as a result of hypogonadism. Male guinea pigs (n=40, 70-72 wk retired breeders) were block randomized by weight into 4 groups: 1) sham surgery (SHAM)/control (CTRL) diet, 2) SHAM/conjugated linoleic acid (CLA) diet (1%), 3) orchidectomy (ORX)/CTRL diet, 4) ORX/CLA diet. Dual-energy x-ray absorptiometry scans were performed at baseline and wk16 to assess body composition.

Source: Nutrition Research - January 5, 2016 Category: Nutrition Authors: Susan Q. Yang, Jason R. DeGuire, Paula Lavery, Ivy L. Mak, Hope A. Weiler, Sylvia Santosa Tags: Original Research Source Type: research