Alloprzeciwciała odpornościowe anty-C po transplantacji krwiotwórczych komórek macierzystych

Publication date: Available online 25 November 2015 Source:Acta Haematologica Polonica Author(s): Lucyna Pawelec-Marzec, Małgorzata Szymczyk-Nużka After multiple transfusions of blood components the patient produced alloantibodies anti-C from the Rh blood group system. These antibodies were the reason of the lack of compatibility of red blood cells of donor's hematopoietic stem cells. After allogeneic hematopoietic stem cell transplantation (allo-HSCT) the presence of anti-C from the Rh group was observed, which may indicate production of these antibodies by residual donor lymphocytes. The presence of anti-c, and subsequently anti-C was the reason of difficulties in the process of matching appropriate red cell concentrate (RCC).
Source: Acta Haematologica Polonica - Category: Hematology Source Type: research