Monoclonal gammopathy: The good, the bad and the ugly

Monoclonal gammopathy of undetermined significance (MGUS) is a condition characterized by the presence of a monoclonal gammopathy (MG) in which the clonal mass has not reached a predefined state in which the condition is considered malignant. It is a precursor to conditions such as multiple myeloma or lymphoma at a rate of ~1%/year. Thus, from a hematologic standpoint, MGUS is a fairly benign condition. However, it is now recognized that organ damage resulting from just the MG without the need MM or lymphoma can occur.

Source: Blood Reviews - December 17, 2015 Category: Hematology Authors: Siobhan V. Glavey, Nelson Leung Tags: Review Source Type: research