Wild‐type phosphatase and tensin homolog deleted on chromosome 10 improved the sensitivity of cells to rapamycin through regulating phosphorylation of Akt in esophageal squamous cell carcinoma

This study explored the possible molecular mechanism of some ESCC cells insensitive to rapamycin and provided a measure for treating ESCC patients with PTEN inactivation using mTOR inhibitors.

Source: Diseases of the Esophagus - January 3, 2016 Category: Gastroenterology Authors: Z. Lu, J. Wang, Y. Zheng, S. Yang, M. Liu, X. Chen, C. Wang, G. Hou Tags: Original Article Source Type: research