Region-Specific Dissociation between Cortical Noradrenaline Levels and the Sleep/Wake Cycle

Conclusions:Locus coeruleus (LC) neurons targeting prefrontal cortex may fatigue more markedly, or earlier, than other LC cells, suggesting one of the mechanisms underlying the cognitive impairment and the increased sleep presure associated with sleep deprivation.Commentary:A commentary on this article appears in this issue on page 11.Citation:Bellesi M, Tononi G, Cirelli C, Serra PA. Region-specific dissociation between cortical noradrenaline levels and the sleep/wake cycle. SLEEP 2016;39(1):143–154.
Source: Sleep - Category: Sleep Medicine Source Type: research