Global and Regional Brain Non-Gaussian Diffusion Changes in Newly Diagnosed Patients with Obstructive Sleep Apnea

Conclusions:Global mean kurtosis values are significantly increased in obstructive sleep apnea (OSA), suggesting acute tissue injury, and these changes are principally localized in critical sites mediating deficient functions in the condition. The mechanisms for injury likely include altered perfusion and hypoxemia-induced processes, leading to acute tissue changes in recently diagnosed OSA.Citation:Tummala S, Palomares J, Kang DW, Park B, Woo MA, Harper RM, Kumar R. Global and regional brain non-gaussian diffusion changes in newly diagnosed patients with obstructive sleep apnea. SLEEP 2016;39(1):51–57.
Source: Sleep - Category: Sleep Medicine Source Type: research