Differentiation therapy: a promising strategy for cancer treatment.
Differentiation therapy: a promising strategy for cancer treatment.
Chin J Cancer. 2016;35(1):3
Authors: Yan M, Liu Q
Abstract
Poor differentiation is an important hallmark of cancer cells, and differentiation therapy holds great promise for cancer treatment. The restoration of IkB kinase α (IKKα) leads to the differentiation of nasopharyngeal carcinoma cells with reduced tumorigenicity. The findings by Yan et al. validate the polycomb protein enhancer of zeste homologue 2 (EZH2) as a target for intervention.
PMID: 26739838 [PubMed - in process]
Source: Chinese Journal of Cancer - Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research